An Unbiased View of Conolidine alkaloid for chronic pain
Most not long ago, it's been discovered that conolidine and the above derivatives act on the atypical chemokine receptor 3 (ACKR3. Expressed in equivalent spots as classical opioid receptors, it binds into a big selection of endogenous opioids. Contrary to most opioid receptors, this receptor acts like a scavenger and will not activate a 2nd messen